Yes, it works. I have c64 (d64 image disks) and AmigaOCS, AmigaAGA, AmigaCD32 and AmigaCDTV working OK.
C64 running with “libretro/vice” core and AmigaOCS/AGA/CD32/CDTV wdhload games running with “libretro/puae” core, but Amiga has some problems in the configuration discussed in the forum (if you change amiga model to emulate some games to require special amiga machine versions, this change affects all core, affecting to all sytems configurations who depends of this core causing conflicts in the configuration)